Synthesis, Characterization, And İnvestigations Of Antimicrobial Activity Of Benzopyrans, Benzofurans And Spiro[4.5]Decanes
Yazarlar (8)
Deniz E. Akpınar Ankara Üniversitesi, Türkiye
Mehtap Özgür (Nee Yakut) Ankara Üniversitesi, Türkiye
Dr. Öğr. Üyesi Hakan ASLAN Sinop Üniversitesi, Türkiye
Doç. Dr. Oğuzhan Alagöz Afyon Kocatepe Üniversitesi, Türkiye
Atilla Öktemer
Ankara Üniversitesi, Türkiye
Prof. Dr. Hakan Dal Anadolu Üniversitesi, Türkiye
Tuncer Hökelek
Hacettepe Üniversitesi, Türkiye
Elif Loğoğlu Gazi Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Synthetic Communications (Q3)
Dergi ISSN 0039-7911 Dergi Bilgileri (2018)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Ingilizce Basım Tarihi 10-2018
Kabul Tarihi Yayınlanma Tarihi 02-10-2018
Cilt / Sayı / Sayfa 48 / 19 / 2510–2521 DOI 10.1080/00397911.2018.1509094
Makale Linki https://www.tandfonline.com/doi/full/10.1080/00397911.2018.1509094
UAK Araştırma Alanları
Organik Kimya
Özet
In this study, the radical cyclization reactions of cyclic 1,3-dicarbonyl compounds (1a–c) and α,β-unsaturated alcohols (2a–d) through Mn(OAc)3 were performed. A series of biologically interesting dihydropyrans (3–5) and dihydrofurans (6–18) were synthesized as a result of these reactions. Spiro compounds (19–20) were obtained from the reactions of 1,3-dicarbonyl compounds and (E)-2,4-diphenyl-but-3-en-2-ol (2e). The unique structure of compound 19 was also confirmed by X-ray crystallography. In addition, the antibacterial activities of synthesized compounds were screened against some bacteria. Their zone diameters showed better results than some known antibiotics.
Anahtar Kelimeler
benzofuran | Benzopyran | cyclization | manganese(III) acetate | spiro[4.5]decane
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 5
Scopus 5
Google Scholar 5
Synthesis, Characterization, And İnvestigations Of Antimicrobial Activity Of Benzopyrans, Benzofurans And Spiro[4.5]Decanes

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