Determination of Trace Element Concentrations in Blood Samples and Their Correlation to Breast Cancer
Yazarlar (8)
Doç. Dr. Ömer Topdağı Atatürk Üniversitesi, Türkiye
Arş. Gör. Ozan Toker Yıldız Teknik Üniversitesi, Türkiye
Prof. Dr. Sezgin Bakırdere Yıldız Teknik Üniversitesi, Türkiye
Ersoy Öz Yıldız Teknik Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ertuğrul Osman BURSALIOĞLU Sinop Üniversitesi, Türkiye
Mohammad Abuqbeıtah
İstanbul Üniversitesi-Cerrahpaşa, Türkiye
İstanbul Üniversitesi-Cerrahpaşa, Türkiye
Mustafa Demir İstanbul Üniversitesi-Cerrahpaşa, Türkiye
Prof. Dr. Orhan İçelli Yıldız Teknik Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | ATOMIC SPECTROSCOPY (Q2) | ||
| Dergi ISSN | 0195-5373 Dergi Bilgileri (2020) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2020 |
| Cilt / Sayı / Sayfa | 41 / 1 / 29–35 | DOI | 10.46770/AS.2020.01.004 |
| Makale Linki | http://www.at-spectrosc.com/as/article/pdf/202001004 | ||
| UAK Araştırma Alanları |
Biyoteknoloji
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| Özet |
| The main purpose of this study was to investigate the possible differences in the concentrations of Al, Cu, Ca, Mg, Fe, Ni, and Pb in breast cancer patients and healthy control group. One blood sample each was collected from 40 adult female patients diagnosed with breast cancer and 40 healthy adult female individuals with no medical history of cancer. The concentrations of the elements Al, Cu, Fe, Ni, and Pb were determined by ICP-MS, while Ca and Mg were determined by ICP-OES. Statistical analysis was performed with the Kolmogorov-Smirnov normality test, the Mann-Whitney U test, and the Spearman’s rank correlation test. It was observed that the concentrations of Cu and Mg in the breast cancer patients were significantly higher (p= 0.000< 0.05 and p= 0.001< 0.05, respectively) than for the healthy group, while the Al concentration was significantly lower (p= 0.002< 0.05) in the cancer patients. The Mg concentration in the control group and the patients was 33.60±4.51 and 38.10±9.69 mg/kg, respectively. The difference was statistically significant for Cu, Mg, and Al, whereas no difference was observed between the concentrations of Ca and Fe. Furthermore, a positive correlation was observed in breast cancer patients between the concentrations of (Al-Cu),(Al-Ca),(Fe-Mg), and (Cu-Ca). |
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BM Sürdürülebilir Kalkınma Amaçları
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| Web of Science | 3 |
| Google Scholar | 5 |