The Effect of Topoisomerase Mutations on the Resistance to the Second Generation Quinolones in Pseudomonas aeruginosa Clinical Isolates
Yazarlar (2)
Doç. Dr. Cumhur AVŞAR Sinop Üniversitesi, Türkiye
Doç. Dr. Zeynep YEĞİN Sinop Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (Diğer hakemli uluslarası dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Research Reviews: Research Journal of Biology | ||
| Dergi ISSN | 2322-0066 | ||
| Dergi Tarandığı Indeksler | Index Copernicus | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2017 |
| Cilt / Sayı / Sayfa | 5 / 1 / 1–5 | DOI | – |
| Makale Linki | https://www.rroij.com/open-access/the-effect-of-topoisomerase-mutations-on-the-resistance-to-thesecond-generation-quinolones-in-pseudomonas-aeruginosa-clinicalisola-.php?aid=85676 | ||
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Tıbbi Biyoloji
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| Özet |
| Pseudomonas aeruginosa is a clinically significant opportunistic pathogen which rarely causes disease in healthy immunocompetent individuals. The emergence of multi-drugresistant strains in P. aeruginosa isolates has increased worlwide. Fluoroquinolones act as bactericidal agents by inhibiting DNA gyrase and topoisomerase IV, thus inhibiting DNA tr... |
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