The Combined Therapy of Teriparatide and Raloxifene Improves Osseointegration of Dental Implants in the Osteoporotic Rabbit Model.
Yazarlar (6)
Ahmet Emin Demirbaş
Firas Mohsen
Cihan Topan
Prof. Dr. Mustafa KARAKAYA Sinop Üniversitesi, Türkiye
Nükhet Kütük
Alper Alkan
Sinop Üniversitesi
Sinop Üniversitesi
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
|
||
| Dergi Adı | International Journal of Oral & Maxillofacial Implants (Q2) | ||
| Makale Dili | – | Basım Tarihi | 05-2024 |
| Cilt / Sayı / Sayfa | 39 / 3 / 435–0 | DOI | – |
| Makale Linki | https://openurl.ebsco.com/contentitem/gcd:178079434?sid=ebsco:plink:crawler-gcd&id=ebsco:gcd:178079434&crl=c&jrnl=08822786 | ||
| UAK Araştırma Alanları |
|
||
| Özet |
| Purpose To evaluate the efficacy of combined therapy of teriparatide and raloxifene on the osseointegration of titanium dental implants in a rabbit model of osteoporotic bone. Materials and Methods Sixty female rabbits were randomly divided into six groups. The sham ovariectomy group (control) consisted of animals that received no medication. Animals in the ovariectomy group (OVX) underwent ovariectomy and received no medication. The combined group consisted of ovariectomized animals that received combined teriparatide (10 mg/kg) for 12 weeks and raloxifene (10 mg/kg) for 12 weeks. The sequential group (SEQ) consisted of ovariectomized animals that received teriparatide (10 mg/kg) for the first 6 weeks and raloxifene therapy (10 mg/kg) for the following 6 weeks sequentially. The parathormone (PTH) and raloxifene (RAL) groups consisted of ovariectomized animals that received only teriparatide (10 … |
| Anahtar Kelimeler |
