Protective effect of cerium oxide on testicular function and oxidative stress after torsion/detorsion in adult male rats
Yazarlar (6)
Suleyman Yesil
Cagri Ozdemir
Mustafa Arslan
Prof. Dr. Ayşe GÜNDOĞDU Sinop Üniversitesi, Türkiye
Mustafa Kavutcu
Prof. Dr. Ali Atan Sinop Üniversitesi
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Experimental and therapeutic medicine (Q3) | ||
| Makale Dili | – | Basım Tarihi | 11-2022 |
| Cilt / Sayı / Sayfa | 25 / 1 / 1–0 | DOI | – |
| Makale Linki | https://www.spandidos-publications.com/etm/25/1/1 | ||
| UAK Araştırma Alanları |
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| Özet |
| Testicular torsion (T)/detorsion (D) can cause testicular injury due to the rotation of the spermatic cord and its vessels, therefore it represents an urological emergency that is surgically treated. Oxidative damage occurs in the testis and distant organs because of the overproduction of free radicals and overexpression of proinflammatory cytokines by reperfusion after surgery. Cerium oxide (CeO2) nanoparticles, a material also known as nanoceria, have regenerative antioxidant properties on oxidative stress. The present study aimed to investigate the effects of nanoceria on testis tissues in testicular T/D in rats. A total of 24 rats were equally and randomly divided into four groups: Control, CeO2, T/D and CeO2-T/D groups. Left inguinoscrotal incision was performed in the control group. In the CeO2 group, 0.5 mg/kg CeO2 was given intraperitoneally 30 min before inguinoscrotal incision. In the T/D group, unilateral … |
| Anahtar Kelimeler |
