Efficacy and acceptability of tianeptine versus sertraline: A multi center, double blind, controlled study
Yazarlar (13)
ET Oral
B Taneli
Z Tunca
A Akdemir
S Vahip
O Dogan
S Sofuoglu
N Dilbaz
I Kirpinar
B Ulug
S Ünal
U Özkutlu
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | European Neuropsychopharmacology (Q1) | ||
| Makale Dili | – | Basım Tarihi | 01-2001 |
| Cilt / Sayı / Sayfa | 11 / 0 / – | DOI | – |
| Makale Linki | https://scholar.google.com/scholar?cluster=11865929154630694090&hl=en&oi=scholarr | ||
| UAK Araştırma Alanları |
Hidrobiyoloji
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| Özet |
| Objective: Lamotrigine, an established anticonvulsant drug, has recently demonstrated efficacy in double-blind, controlled clinical trials in bipolar depression and rapid cycling bipolar disorder. The current study was designed to evaluate the long-term efficacy and safety of lamotrigine as a mood stabilizer in preventing relapse in patients with a current or recent (within past two months) DSM-IV diagnosis of mania or hypomania. Methods: GW Study# 606 was an international, multicentre, double-blind, placebo-controlled, flexible-dose study conducted in bipolar I outpatients. 349 patients were entered into a preliminary open-label phase during which lamotrigine (up to 200 mg/day) was used as add-on or monotherapy for up to 16 weeks followed by withdrawal to lamotrigine monotherapy prior to randomization. A total of 175 patients achieving stabilization (defined as CGI-S 5 3 for 4 consecutive weeks) were then … |
| Anahtar Kelimeler |
