Lack of association between MAOA-uVNTR variants and excessive daytime sleepiness
Yazarlar (6)
Filiz Özen
Istanbul Medeniyet University, Türkiye
Istanbul Medeniyet University, Türkiye
Doç. Dr. Zeynep YEĞİN Sinop Üniversitesi, Türkiye
Figen Yavlal
Bahçeşehir Üniversitesi, Türkiye
Bahçeşehir Üniversitesi, Türkiye
Zuhal Aydan Sağlam
Istanbul Medeniyet University, Türkiye
Istanbul Medeniyet University, Türkiye
Doç. Dr. Haydar Koç Çankırı Karatekin Üniversitesi, Türkiye
İsmet Berber
Sinop Üniversitesi, Türkiye
Sinop Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Neurological Sciences (Q3) | ||
| Dergi ISSN | 1590-1874 Dergi Bilgileri (2017) | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2017 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 08-02-2017 |
| Cilt / Sayı / Sayfa | 38 / 5 / 769–774 | DOI | 10.1007/s10072-017-2836-6 |
| Makale Linki | http://dx.doi.org/10.1007/s10072-017-2836-6 | ||
| UAK Araştırma Alanları |
Tıbbi Biyoloji
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| Özet |
| Sleep disorders are highly prevalent in the population and have dramatic health, social, and economic impacts. However, their treatments may remain symptomatic due to ignorance of molecular factors which may provide fundamental insights into the neurological bases of sleep. Excessive daytime sleepiness (EDS) is a common complaint encountered in neurological practice with significant effects both on individuals and on society. We aimed to investigate the role of monoamine oxidase A (MAOA) as a candidate gene in EDS. Epworth sleepiness scale (ESS) was applied to 221 subjects who were also genotyped for MAOA upstream variable number of tandem repeats (MAOA-uVNTR). Patient group displayed higher ESS values (mean 12.67) when compared with the control group (mean 6.38). However, MAOA-uVNTR genotypes did not show a significant association with ESS scores neither on women nor on … |
| Anahtar Kelimeler |
| Excessive daytime sleepiness | MAOA-uVNTR | Monoamine oxidase A | Neurogenetics | Sleep | Variable number tandem repeat |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 1 |
| Google Scholar | 4 |