Association analysis of Epworth Sleepiness Scale (ESS) scores with serotonin transporter (5-HTT- LPR, 5-HTT-VNTR) and circadian (PER3-VNTR) genes
Yazarlar (6)
Filiz Özen
Istanbul Medeniyet University, Türkiye
Istanbul Medeniyet University, Türkiye
Doç. Dr. Zeynep YEĞİN Sinop Üniversitesi, Türkiye
Zuhal Aydan Sağlam
T. C. Sağlık Bakanlığı, Taksim Eğitim ve Araştirma Hastanesi, Türkiye
T. C. Sağlık Bakanlığı, Taksim Eğitim ve Araştirma Hastanesi, Türkiye
Figen Yavlal
Beykent Üniversitesi, Türkiye
Beykent Üniversitesi, Türkiye
Doç. Dr. Haydar Koç Çankırı Karatekin Üniversitesi, Türkiye
Celal Ulaşoğlu
Istanbul Medeniyet University, Türkiye
Istanbul Medeniyet University, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Sleep Science | ||
| Dergi ISSN | 1984-0659 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | Scopus | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-03-2022 |
| Cilt / Sayı / Sayfa | 15 / 1 / 110–115 | DOI | 10.5935/1984-0063.20220003 |
| Makale Linki | https://www.sleepscience.org.br/details/3153/en-US/association-analysis-of-epworth-sleepiness-scale--ess--scores-with-serotonin-transporter--5-htt--lpr--5-htt-vntr--and-circadian--per3-vntr--genes | ||
| UAK Araştırma Alanları |
Tıbbi Biyoloji
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| Özet |
| Excessive daytime sleepiness (EDS) is a common complaint encountered in clinical practice with serious consequences both for individual and society since it can increase the ratio of motor vehicle accidents, work- related incidents, and deaths. Moreover, it also manifests less serious individual consequences. This study aimed to investigate the potential role of PER3-VNTR, 5-HTT-LPR, and 5-HTT-VNTR in terms of constituting liability to EDS. Two hundred eighteen participants (93 complaining about daytime sleepiness and 125 individuals with no serious complaint) were recruited in the study. General daytime of sleepiness was quantified with Epworth sleepiness scale (ESS). DNA extractions were performed from collected blood samples with standart salting-out procedure and genotyped. ESS scores displayed difference between individuals suffering from sleep disturbances and other individuals with values of … |
| Anahtar Kelimeler |
| Epworth sleepiness scale (ESS) | Excessive daytime sleepiness (EDS) | Genetic association | Neurogenetics | PER3 | Serotonin transporter (5-HTT) |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 3 |
| Google Scholar | 6 |