Diazenyl-hydrazone functionalized silatrane hybrids: Integrating structural precision for Al (III) sensing and anticancer activity
Yazarlar (9)
Gurjaspreet Singh
Panjab University, Hindistan
Panjab University, Hindistan
Heena
Panjab University, Hindistan
Panjab University, Hindistan
Dr. Öğr. Üyesi Seher MERAL Sinop Üniversitesi, Türkiye
Pallavi Markan
Panjab University, Hindistan
Panjab University, Hindistan
Harshbir Kaur
Panjab University, Hindistan
Panjab University, Hindistan
Baljinder Singh Gill
Central University Of Punjab, Hindistan
Central University Of Punjab, Hindistan
Deepanjali Baliyan
Central University Of Punjab, Hindistan
Central University Of Punjab, Hindistan
Vikas
Panjab University, Hindistan
Panjab University, Hindistan
Prof. Dr. Necmi Dege Ondokuz Mayis Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure (Q2) | ||
| Dergi ISSN | 0022-2860 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2026 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-02-2026 |
| Cilt / Sayı / Sayfa | 1352 / 1 / 144486– | DOI | 10.1016/j.molstruc.2025.144486 |
| Makale Linki | https://doi.org/10.1016/j.molstruc.2025.144486 | ||
| UAK Araştırma Alanları |
Fiziksel Kimya
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| Özet |
| This manuscript investigates the synthesis and potential of a silatrane-tethered hydrazone derivative as a multifunctional compound capable of selective metal ion sensing, anticancer activity. The synthesized compound demonstrated high sensitivity and selectivity for Al(III) through UV-Vis and fluorescence spectroscopy with 18.73 and 3.46 nM LOD values, respectively, highlighting its effectiveness as a chemosensor. Additionally, both in-vitro and in-silico studies confirmed its promising anticancer properties. The integration of the silatrane framework with the hydrazone moiety enhanced the stability and optical properties of the compound, positioning it as a versatile candidate for addressing key challenges in environmental monitoring and therapeutic interventions. The results indicate that the silatrane-tethered hydrazone holds significant promise for applications in metal ion detection, cancer treatment, providing a … |
| Anahtar Kelimeler |
| Al(III) Detection | Anticancer Activity | In-silico Studies | In-vitro Studies | Silatrane |
Science Direct
Diazenyl-hydrazone functionalized silatrane hybrids: Integrating structural precision for Al (III) sensing and anticancer activity
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| Atıf Sayıları | |
| Google Scholar | 1 |