Synthesis, characterization, antimicrobial activity, and QSAR studies of some new 6-substituted phenyl 3-(4-chlorophenyl)-3a,4,8,8a-tetrahydro-[1,3,2]dioxaborepino [5,6-d]isoxazoles
Yazarlar (1)
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Heteroatom Chemistry (Q3) | ||
| Dergi ISSN | 1042-7163 Dergi Bilgileri (2017) | ||
| Dergi Tarandığı Indeksler | |||
| Makale Dili | İngilizce | Basım Tarihi | 01-2017 |
| Cilt / Sayı / Sayfa | 28 / 2 / – | DOI | 10.1002/hc.21363 |
| Makale Linki | http://www.scopus.com/inward/record.url?eid=2-s2.0-85010737655&partnerID=MN8TOARS | ||
| UAK Araştırma Alanları |
Fen Bilimleri ve Matematik
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| Özet |
| 3‐(4‐Chlorophenyl)‐3a,4,8,8a‐tetrahydro‐[1,3,2]dioxaborepino[5,6‐d] isoxazoles were synthesized from the reaction of (3‐(4‐chlorophenyl)‐4,5‐dihydroisoxazole‐4,5‐diyl)dimethanol with substituted phenylboronic acids. Crystal structure of 1‐(4‐(3‐(4‐chlorophenyl)‐3a,4,8,8a‐tetrahydro‐[1,3,2]dioxaborepino[5,6‐d]isoxazol‐6‐yl)phenyl) ethanone was studied and the values of selected bond distances (Å), bond angles (°), and dihedral angles (°) were found in agreement with the calculated (DFT, B3LYP/6‐311++G(d,p)) values. Antimicrobial activity of these new compounds was also studied against a panel of microorganisms including Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, Streptococcus mutans, and Candida albicans. Most of the dioxaborepines exhibited fair activities against these microorganisms. The pMIC values of the compounds were first correlated … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 5 |
| Scopus | 6 |
| Google Scholar | 9 |