Biochemical Effects of Long-Term Exercise on Oxidative Stress and Antioxidant Markers in Adolescent Female Athletes
Yazarlar (10)
Ömer Faruk Bilici
Marmara Üniversitesi, Türkiye
Dilara Erkan
Ankara Üniversitesi, Türkiye
Dan Iulian Alexe
Universitatea Din Bacau, Romanya
Dragoș Ioan Tohănean
Universitatea Transilvania Din Brașov, Romanya
Doç. Dr. Canan Demir Van Yüzüncü Yıl Üniversitesi, Türkiye
Cristina Ioana Alexe
Universitatea Din Bacau, Romanya
Virgil Ene Voiculescu Academia Navala "Mircea Cel Batran", Romania, Romanya
Prof. Dr. Muhammed Fatih Bilici Muş Alparslan Üniversitesi, Türkiye
Héctor Fuentes-Barria Universidad Arturo Prat, Şili
Doç. Dr. Ulaş Can YILDIRIM Sinop Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Children (Q1)
Dergi ISSN 2227-9067 Dergi Bilgileri (2025)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 06-2025
Kabul Tarihi – Yayınlanma Tarihi 20-06-2025
Cilt / Sayı / Sayfa 12 / 7 / 809–0 DOI 10.3390/children12070809
Makale Linki https://doi.org/10.3390/children12070809
UAK Araştırma Alanları
Ergojenik Yardım ve Doping Antrenman Bilimi Egzersiz ve Spor Fizyolojisi
Özet
Background Adolescence is a critical period where exercise-induced oxidative stress is modulated by both training adaptations and hormonal changes, particularly the antioxidant effects of estrogen in females. However, data on how adolescent female athletes respond to long-term exercise remain limited. The aim of this study was to examine oxidative stress levels and some antioxidant defense parameters in adolescent female athletes who train regularly. Methods The study included 20 adolescent female basketball players (16.65 ± 0.67 years; 165.50 ± 0.06 cm; 59.75 ± 5.50 kg) with at least three years of training experience and 20 non-athlete adolescent female participants (16.80 ± 0.69 years; 159.95 ± 0.04 cm; 60.15 ± 4.23 kg). Malondialdehyde (MDA), glutathione (GSH), and catalase (CAT) levels were analyzed by a spectrophotometric method using a UV/VIS spectrophotometer in blood samples taken from all participants, and the data were compared between the groups. Results The results showed that MDA levels were significantly lower in the athlete group (p < 0.01; d = 4.78). In addition, CAT activity was significantly higher in athletes compared to non-athletes (p < 0.01; d = 7.81). However, no significant difference was observed in GSH levels between the groups (p > 0.05; d = 0.15). A strong negative correlation was found between MDA and CAT (r = −0.900). Conclusions These findings suggest that prolonged exercise reduces oxidative stress and enhances catalase-mediated antioxidant defense in adolescent women. Increased CAT activity and decreased MDA levels support this effect, while stable GSH levels point to the role of …
Anahtar Kelimeler
adolescent | antioxidants | athletes | exercise | female | oxidative stress
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 4
Scopus 4
Google Scholar 5
Biochemical Effects of Long-Term Exercise on Oxidative Stress and Antioxidant Markers in Adolescent Female Athletes

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