In vitro cytotoxicity of hydrothermally synthesized ZnO nanoparticles on human periodontal ligament fibroblast and mouse dermal fibroblast cells
Yazarlar (5)
Doç. Dr. Şükran Şeker Ankara Üniversitesi, Türkiye
A. Eser Elçin
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
Doç. Dr. Tuğrul YUMAK Sinop Üniversitesi, Türkiye
Ali Sinaǧ
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
Y. Murat Elçin
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Toxicology in Vitro (Q2) | ||
| Dergi ISSN | 0887-2333 Dergi Bilgileri (2014) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2014 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-12-2014 |
| Cilt / Sayı / Sayfa | 28 / 8 / 1349–1358 | DOI | 10.1016/j.tiv.2014.06.016 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0887233314001313 | ||
| UAK Araştırma Alanları |
Fiziksel Kimya
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| Özet |
| The use of metal oxide nanoparticles (NPs) in industrial applications has been expanding, as a consequence, risk of human exposure increases. In this study, the potential toxic effects of zinc oxide (ZnO) NPs on human periodontal ligament fibroblast cells (hPDLFs) and on mouse dermal fibroblast cells (mDFs) were evaluated in vitro. We synthesized ZnO NPs (particle size; 7–8 nm) by the hydrothermal method. Characterization assays were performed with atomic force microscopy, Braun–Emmet–Teller analysis, and dynamic light scattering. The hPDLFs and mDFs were incubated with the NPs with concentrations of 0.1, 1, 10, 50 and 100 μg/mL for 6, 24 and 48 h. Under the control and NP-exposed conditions, we have made different types of measurements for cell viability and morphology, membrane leakage and intracellular reactive oxygen species generation. Also, we monitored cell responses to ZnO NPs using … |
| Anahtar Kelimeler |
| Dermal fibroblasts | Impedance measurement | Nanoparticles | Periodontal ligament fibroblasts | Toxicity | Zinc oxide |
Science Direct
In vitro cytotoxicity of hydrothermally synthesized ZnO nanoparticles on human periodontal ligament fibroblast and mouse dermal fibroblast cells
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 51 |
| Scopus | 59 |
| Google Scholar | 74 |