Synthesis, characterization, antioxidant, and antibacterial activities of new 2,3-dimethoxy and 3-acetoxy-2-methyl benzamides
Yazarlar (5)
Doç. Dr. Hasan Yakan Ondokuz Mayıs Üniversitesi, Türkiye
Doç. Dr. Şükriye ÇAKMAK Sinop Üniversitesi, Türkiye
Prof. Dr. Halil Kütük Ondokuz Mayis University Faculty Of Science And Arts, Türkiye
Semiha Yenigün Ondokuz Mayis University Faculty Of Science And Arts, Türkiye
Prof. Dr. Tevfik Özen Ondokuz Mayıs Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Research on Chemical Intermediates (Q2) | ||
| Dergi ISSN | 0922-6168 Dergi Bilgileri (2020) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2020 |
| Cilt / Sayı / Sayfa | 46 / 5 / 2767–2787 | DOI | 10.1007/s11164-020-04118-7 |
| Makale Linki | http://link.springer.com/10.1007/s11164-020-04118-7 | ||
| UAK Araştırma Alanları |
Organik Kimya
Spektroskopi
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| Özet |
| We performed a series of novel benzamide compounds which were synthesized starting from 2,3-dimethoxybenzoic acid or 3-acetoxy-2-methylbenzoic acid and amine derivatives. All the obtained products were purified, and the analysis of these products was determined with IR, 1H NMR, 13C NMR spectroscopic, and elemental methods. The in vitro antioxidant activity of all the compounds was determined by total antioxidant, free radical scavenging, and metal chelating activity. Some of synthesized compounds showed more effective total antioxidant, free radical scavenging, and metal chelating activity compared with standards. One of the benzamide compounds has been shown to exhibit effective metal chelate activity. The new compounds were determined in vitro antibacterial activity against three gram-positive bacteria and three gram-negative bacteria and compared with two control drugs. Thus, by conducting … |
| Anahtar Kelimeler |
| Amides | Antibacterial activity | Antioxidant activity | Metal chelating activity | N-acylation | Spectroscopic techniques |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 19 |
| Scopus | 20 |
| Google Scholar | 26 |