Synthesis of axially disubstituted silicon phthalocyanines and investigation of photodynamic effects on HCT-116 colorectal cancer cell line
Yazarlar (4)
Ceren Sarı Karadeniz Teknik Üniversitesi, Türkiye
Figen Celep Eyüpoğlu Karadeniz Teknik Üniversitesi, Türkiye
Prof. Dr. İsmail Değirmencioğlu Karadeniz Teknik Üniversitesi, Türkiye
Prof. Dr. Rıza BAYRAK Sinop Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Photodiagnosis and Photodynamic Therapy (Q3) | ||
| Dergi ISSN | 1572-1000 Dergi Bilgileri (2018) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 09-2018 |
| Cilt / Sayı / Sayfa | 23 / 1 / 83–88 | DOI | 10.1016/j.pdpdt.2018.05.009 |
| Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S1572100018300176 | ||
| UAK Araştırma Alanları |
Anorganik Kimya
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| Özet |
| Photodynamic therapy is one of the hot topics in cancer studies. Photosensitizing chemical substrates are stimulated by light having a specific wavelength to cause fatal effect on different kinds of targets.In this study, axially 4-{[(1E)-2-furylmethylene]amino}phenol, 4-{[(1E)-2-thienylmethylene]amino}phenol and 4-{[(1E)-(4-nitro-2-thienyl)methylene]amino}phenol disubstituted silicon phthalocyanines were synthesized as Photosensitizers for photodynamic therapy in cancer treatment. The structural characterizations of these novel compounds were performed by a combination of FT-IR, 1H-NMR, UV–vis and mass. All these newly prepared compounds did not show aggregation at the concentration range of 2 × 10−6−12 × 10−6 M in tetrahydrofurane and also did not show aggregation in different organic solvents at 2 × 10−6 M concentration.Phthalocyanines synthesized in this study were tested on HCT-116 … |
| Anahtar Kelimeler |
| Colorectal cancer | HCT-116 | Photodynamic therapy | Silicon phthalocyanine | Synthesis |
Science Direct
Synthesis of axially disubstituted silicon phthalocyanines and investigation of photodynamic effects on HCT-116 colorectal cancer cell line
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 15 |
| Scopus | 16 |
| Google Scholar | 19 |