Nucleic acids oxidative stress status in sjögren’s syndrome.
Yazarlar (4)
Duygu Tecer Türkiye
Dr. Öğr. Üyesi Rabia TURAL Sinop Üniversitesi, Türkiye
Aylin Sepici Dinçel Gazi Üniversitesi, Türkiye
Feride Göğüş
| Makale Türü |
Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği,
araştırma notu, bilirkişi raporu ve benzeri)
(SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not,
editöre mektup, tartışma, vaka takdimi ve özet türünden makale)
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| Dergi Adı | ANNALS OF THE RHEUMATIC DISEASES (Q1) | ||
| Dergi ISSN | 0003-4967 Dergi Bilgileri (2017) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 06-2017 |
| Cilt / Sayı / Sayfa | 76 / 0 / 1223–1223 | DOI | 10.1136/annrheumdis-2017-eular.3286 |
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| BackgroundAlthough there are many defence systems that protect cellular macromolecules against oxidation, oxidative DNA and RNA damage still occurs. Oxidative damage to nucleic acids has been found to be associated with etiopathogenesis and disease activity of inflammatory disorders. Oxidised guanine species have been recognized as a biomarker of oxidative DNA and RNA damage by endogenously generated oxygen radicals. Sjögren's syndrome (SS) is an autoimmune disorder and associated with overexpression of proinflammatory cytokines. Related to excess expression of proinflammatory cytokines, a prooxidant state could be postulated in SS.ObjectivesWe aimed to evaluate levels of nucleic acids oxidative stress products in patients with SS.Methods11 patients with SS diagnosed according to 2012 American College of Rheumatology (ACR) Classification Criteria for Sjögren's Syndrome, 19 … |
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BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 1 |