| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale) | ||
| Dergi Adı | JOURNAL OF THE NEUROLOGICAL SCIENCES (Q3) | ||
| Dergi ISSN | 0022-510X Dergi Bilgileri (2017) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 10-2017 |
| Cilt / Sayı / Sayfa | 381 / 0 / 430–430 | DOI | 10.1016/j.jns.2017.08.3426 |
| UAK Araştırma Alanları |
Tıbbi Biyokimya
|
||
| Özet |
| Background: Migraine is a common neurological disorder and its mechanism haven’t been understood. It has been promised that; neurogenic inflammation, cortical spreading depression, central sensitization and vascular involvement causes pain during migraine attacks. Various neuropeptides, cytokines and chemokines have been shown to mediate nociceptive effects. Brain derived neurotrophic factor (BDNF) is a neurotrophin that has been implicated in the modulation of pain signaling. It is expressed in trigeminal ganglion neurons. On the other hand sirtuin 1 (SIRT1) is a member of the hystone deacetylase family proteins and a key regulator of DNA damage, cell survival, metabolism, synaptic plasticity, memory formation, autophagy and neurodegeneration. It modulates BDNF expression and could contribute to pain.Objective: Our objective is to examine the serum levels of this molecules in migraine patients … |
| Anahtar Kelimeler |
| Atıf Sayıları | |
| Web of Science | 2 |
| Google Scholar | 2 |
| Dergi Adı | JOURNAL OF THE NEUROLOGICAL SCIENCES |
| Kısa Adı | J NEUROL SCI |
| Yayıncı | ELSEVIER SCIENCE BV |
| Açık Erişim | Hayır |
| ISSN | 0022-510X |
| E-ISSN | 1878-5883 |
| Wos Quartile | Q3 |
| Scopus Quartile | Q2 |
| Tarandığı Indeksler | SCIE , Scopus |
| WoS Kategoriler | CLINICAL NEUROLOGY | NEUROSCIENCES |
| Scopus Kategoriler | NEUROLOGY | NEUROLOGY (CLINICAL) |