Determination of endocrine disrupting effects of the antifouling pyrithiones on zebrafish (Danio rerio)
Yazarlar (5)
Prof. Dr. Aysel Çağlan Günal Gazi Üniversitesi, Türkiye
Doç. Dr. Pinar Arslan Çankiri Karatekin Üniversitesi, Türkiye
Nagehan Ipiçürük Gazi University, Faculty Of Medicine, Türkiye
Dr. Öğr. Üyesi Rabia TURAL Sinop Üniversitesi, Türkiye
Aylin Sepici Dinçel Gazi Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Energy Ecology and Environment | ||
| Dergi ISSN | 2363-7692 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Ingilizce | Basım Tarihi | 03-2022 |
| Cilt / Sayı / Sayfa | 7 / 5 / 523–531 | DOI | 10.1007/s40974-022-00245-6 |
| Makale Linki | http://dx.doi.org/10.1007/s40974-022-00245-6 | ||
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| Bacteria, algae, and fungi are the organisms affected by biocidal substances, which are widely used. Apart from these, they can also have toxic effects on various aquatic organisms. Copper pyrithione (CPT) and zinc pyrithione (ZPT) are used as an alternative to tributyltin, which is forbidden and known to be highly toxic to the aquatic ecosystem. However, there is lacking information about histopathological alterations and endocrine disrupting effects of these substances. Therefore, this study was aimed to investigate the effects of ZPT, CPT, and their mixtures on the histological changes in the tissues and on the vitellogenin hormone in male zebrafish. Substances caused hyperemia, epithelial lifting, telangiectasis, and hyperplasia in the gill tissue. In the liver tissue, hyperemia, hydropic degeneration and necrosis were observed. In addition, apoptosis was found in the gill, liver, and testicle of the tissues as a result of … |
| Anahtar Kelimeler |
| Copper pyrithione | Danio rerio | Endocrine disruptors | Histological alterations | Vitellogenin | Zinc pyrithione |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 5 |
| Scopus | 5 |
| Google Scholar | 7 |