Does bisphenol A bioaccumulate on zebrafish? Determination of tissue bisphenol A level
Yazarlar (4)
Burcu Eser University Of Health Sciences, Türkiye
Dr. Öğr. Üyesi Rabia TURAL Sinop Üniversitesi, Türkiye
Prof. Dr. Aysel Çağlan Günal Gazi Üniversitesi, Türkiye
Aylin Sepici Dinçel Gazi University, Faculty Of Medicine, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Biomedical Chromatography (Q3) | ||
| Dergi ISSN | 0269-3879 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Ingilizce | Basım Tarihi | 03-2022 |
| Cilt / Sayı / Sayfa | 36 / 3 / – | DOI | 10.1002/bmc.5285 |
| Makale Linki | http://dx.doi.org/10.1002/bmc.5285 | ||
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| Bisphenol A (BPA) is a high‐production‐volume industrial chemical mainly used in the production of polycarbonates and epoxy resins utilized in the manufacture of containers, bottles, toys, and medical devices. It has systemic effects as an endocrine disruptor even at low doses. To analyze its quantity in biological materials, sensitive and reproducible methods have to be used. Different doses and duration (90 and 900 μg/L, 24 and 120 h, and 21 days) of BPA exposure to whole body zebrafish were analyzed after specific homogenization of tissue, and then a modified method HPLC was used. The mobile phase was acetonitrile and water using a gradient method of reversed‐phase C18 column, and excitation = 227 nm/emission = 313 nm. The calibration curve for BPA using HPLC‐fluorescence detection method was between a concentration range of 1 and 1000 ng/mL and linear, and r2 = 0.999. The … |
| Anahtar Kelimeler |
| bioaccumulation | bisphenol A | endocrine-disrupting chemicals | HPLC | zebrafish |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 3 |
| Scopus | 5 |
| Google Scholar | 6 |