SYNTHESIS CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI N CINNAMYL FLUOXETINECHLORIDE
Yazarlar (5)
Nosheen Kanwal
Lahore College For Women University, Pakistan
Prof. Dr. Onur ŞAHİN Ondokuz Mayis University Faculty Of Science And Arts, Türkiye
Erum A. Husaain
Lahore College For Women University, Pakistan
Islam Ullah Khan
Government College University Lahore, Pakistan
Orhan Buyukgungor
Ondokuz Mayis University Faculty Of Science And Arts, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of the Chilean Chemical Society
Dergi ISSN 0717-9324
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2013
Cilt / Sayı / Sayfa 58 / 1 / 1508–1512 DOI 10.4067/S0717-97072013000100001
UAK Araştırma Alanları
Yoğun Madde Fiziği
Özet
A new derivative of Fluoxetine, N, N-dicinnamyl-N-methyl-3-phenyl-3-[4-(trifluoromethyl) phenoxy] butan-1-aminium chloride hydrate [Di-(N-Cinnamyl) Fluoxetine Chloride hydrate] was synthesized and characterized by single-crystal X-ray diffraction studies, elemental analyzer, thermogravimetric and FTIR spectroscopy analysis. The titled compound [C 35 H 37 ClF 3 NO 2] crystallized in monoclinic, having unit cell parameters a= 19.155 (14) A, b= 9.193 (5) A, c= 18.596 (13) Aand belongs to P2 1/c space group. The molecule shows disorder of F atoms and was modeled as two different orientations. The one-dimensional crystal packing features weak C-H… π interactions showing the formation of a chain along [001], provides stability to the crystal lattice. Antioxidant potential of Di-(N-Cinnamyl) Fluoxetine Chloride hydrate has been described and was found higher than Fluoxetine and N-Benzyl Fluoxetine.
Anahtar Kelimeler
Antioxidant activity | Crystal structure | Derivative | Fluoxetine
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 3
Scopus 2
Google Scholar 3
Google Scholar 3
SYNTHESIS CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI N CINNAMYL FLUOXETINECHLORIDE

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