Synthesis and description of intermolecular interactions in new sulfonamide derivatives of tranexamic acid
Yazarlar (9)
Muhammad Ashfaq
University Of Gujrat, Pakistan
University Of Gujrat, Pakistan
Muhammad Nadeem Arshad
Faculty Of Sciences, King Abdulaziz University, Suudi Arabistan
Faculty Of Sciences, King Abdulaziz University, Suudi Arabistan
Muhammad Danish
University Of Gujrat, Pakistan
University Of Gujrat, Pakistan
Abdullah M Asiri
Faculty Of Sciences, King Abdulaziz University, Suudi Arabistan
Faculty Of Sciences, King Abdulaziz University, Suudi Arabistan
Sadia Khatoon
University Of Gujrat, Pakistan
University Of Gujrat, Pakistan
Ghulam Mustafa
University Of Gujrat, Pakistan
University Of Gujrat, Pakistan
Pavel N Zolotarev
Samara National Research University, Rusya Federasyonu
Samara National Research University, Rusya Federasyonu
Rabia Ayub Butt
University Of Gujrat, Pakistan
University Of Gujrat, Pakistan
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure (Q3) | ||
| Dergi ISSN | 0022-2860 Dergi Bilgileri (2016) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 1103 / 1 / 271–280 | DOI | 10.1016/j.molstruc.2015.09.022 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0022286015302854 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| Abstract Tranexamic acid (4-aminomethyl-cyclohexanecarboxylic acid) was reacted with sulfonyl chlorides to produce structurally related four sulfonamide derivatives using simple and environmental friendly method to check out their three-dimensional behavior and van der Walls interactions. The molecules were crystallized in different possibilities, as it is/after alkylation at its O and N atoms/along with a co-molecule. All molecules were crystallized in monoclinic crystal system with space group P2 1/n, P2 1/c and P2 1/a. X-ray studies reveal that the molecules stabilized themselves by different kinds of hydrogen bonding interactions. The molecules are getting connected through O–H⋯ O hydrogen bonds to form inversion dimers which are further connected through N–H⋯ O interactions. The molecules in which N and O atoms were alkylated showed non-classical interaction and generated centro-symmetric R 2 2 (24 … |
| Anahtar Kelimeler |
| Crystallization | Sulfonamide | Topological aspects of structure | Tranexamic acid |
Science Direct
Synthesis and description of intermolecular interactions in new sulfonamide derivatives of tranexamic acid
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 5 |
| Scopus | 5 |
| Google Scholar | 6 |