Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with iN/i -salicyloil- iN/i ′-maleoil-hydrazine as anticholinergic and antidiabetic agents/title
Yazarlar (10)
Gulnar Gondolova
Azerbaijan National Academy Of Sciences, Azerbaycan
Azerbaijan National Academy Of Sciences, Azerbaycan
Doç. Dr. Parham Taslimi Atatürk Üniversitesi, Türkiye
Ajdar Medjidov Azerbaijan National Academy Of Sciences, Azerbaycan
Vagif Farzaliyev
Azerbaijan National Academy Of Sciences, Azerbaycan
Azerbaijan National Academy Of Sciences, Azerbaycan
Afsun Sujayev
Azerbaijan National Academy Of Sciences, Azerbaycan
Azerbaijan National Academy Of Sciences, Azerbaycan
Mansura Huseynova
Azerbaijan National Academy Of Sciences, Azerbaycan
Azerbaijan National Academy Of Sciences, Azerbaycan
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Prof. Dr. Bahattin Yalçın Marmara Üniversitesi, Türkiye
Doç. Dr. Fikret Turkan Iğdır Üniversitesi, Türkiye
Prof. Dr. Ilhami Gulçin Atatürk Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Biochemical and Molecular Toxicology (Q2) | ||
| Dergi ISSN | 1095-6670 Dergi Bilgileri (2018) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 09-2018 |
| Kabul Tarihi | 25-06-2018 | Yayınlanma Tarihi | 25-07-2018 |
| Cilt / Sayı / Sayfa | 32 / 9 / 22197–0 | DOI | 10.1002/jbt.22197 |
| Makale Linki | http://doi.wiley.com/10.1002/jbt.22197 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| [Ni(C11H9N2O5)2(H2O)2]•3(C3H7NO) (1) and [Co(C11H9N2O5)2(H2O)2]•3(C3H7NO) (2) are synthesized and characterized by elemental analysis, FT‐IR spectra, magnetic susceptibility, and thermal analysis. In addition, the crystal structure of Ni(II) complex is presented. Both complexes show distorted octahedral geometry. In 1 and 2, metal ions are coordinated by two oxygen atoms of salicylic residue and two nitrogen atoms of maleic amide residue from two ligands, and two oxygen atoms from two water molecules. In this paper, both compounds showed excellent inhibitory effects against human carbonic anhydrase (hCA) isoforms I, and II, α‐glycosidase, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE). Compounds 1 and 2 had Ki values of 18.36 ± 4.38 and 26.61 ± 7.54 nM against hCA I and 13.81 ± 3.02 and 29.56 ± 6.52 nM against hCA II, respectively. On the other hand, their Ki values were … |
| Anahtar Kelimeler |
| crystal structure | enzyme inhibition | magnetic properties | N-salicyloil-N’-maleoil-hydrazine | synthesis |
| Atıf Sayıları | |
| Web of Science | 44 |
| Scopus | 49 |
| Google Scholar | 53 |