Water-soluble binary and ternary palladium(II) complexes containing amino acids and intercalating ligands: synthesis, characterization, biomolecular interactions and cytotoxicities
Yazarlar (5)
Duygu İnci
Bursa Uludağ Üniversitesi, Türkiye
Bursa Uludağ Üniversitesi, Türkiye
Prof. Dr. Rahmiye Aydın Bursa Uludağ Üniversitesi, Türkiye
Prof. Dr. Özgür Vatan Bursa Uludağ Üniversitesi, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Prof. Dr. Nilüfer Çinkılıç Bursa Uludağ Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | New Journal of Chemistry (Q2) | ||
| Dergi ISSN | 1144-0546 Dergi Bilgileri (2019) | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2019 |
| Cilt / Sayı / Sayfa | 43 / 12 / 4681–4697 | DOI | 10.1039/c8nj05934a |
| Makale Linki | http://xlink.rsc.org/?DOI=C8NJ05934A | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| In this study, six water soluble cationic binary (1–3) palladium(ıı) complexes of the type [PdA2](NO3)2(n − 1)H2O and ternary (4–6) palladium(ıı) complexes of the type [PdA(amino acid)](NO3)(n − 1)H2O, where A is 1,10-phenanthroline (phen) (1, 4, 6), 5-methyl-1,10-phenanthroline (5-mphen) (2, 5), and 3,4,7,8-tetramethyl-1,10-phenanthroline (tmphen) (3) and the amino acid is L-tyrosine (tyr) (4, 5) and glycine (gly) (6), have been synthesized and characterized using CHN elemental analyses, ATR-FT-MIR, 1H NMR and 13C NMR and single-crystal X-ray diffraction techniques. The interaction of the complexes with calf thymus DNA (CT-DNA) was investigated using electronic absorption spectral, ethidium bromide (EB) and Hoechst 33258 (HO) displacement assays and thermal denaturation. The pUC19 DNA cleavage activity of the complexes was investigated in the absence and presence of external agents by … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 18 |
| Scopus | 18 |
| Google Scholar | 20 |