Synthesis, characterization and anticancer activity in vitro evaluation of novel dicyanoaurate (I)-based complexes
Yazarlar (6)
Prof. Dr. Ahmet Karadağ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Ali Aydın Bozok Üniversitesi, Türkiye
Prof. Dr. Şaban Tekin Sağlık Bilimleri Üniversitesi, Türkiye
Hüseyin Akbaş Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Prof. Dr. Fatih Şen Dumlupinar Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Life Sciences (Q1) | ||
| Dergi ISSN | 0024-3205 Dergi Bilgileri (2020) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2020 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-06-2020 |
| Cilt / Sayı / Sayfa | 251 / 1 / 117635–0 | DOI | 10.1016/j.lfs.2020.117635 |
| Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S0024320520303830 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| Molecular structures containing gold, such as auranofin, have been extensively studied in the diagnosis and treatment of many diseases, including cancer treatment. The pharmacological properties of the newly synthesized unique gold-ligand structures have been reported for different cancer cell lines. However, findings on bishydeten-metal salt complexes with gold are rare. In this work, the synthesis of five novel cyanide-bridged coordination compounds having the closed formulae [Ni(bishydeten)][Au(CN)2]2 (1), [Cu(bishydeten)][Au(CN)2]2 (2), [Zn(bishydeten)2Au3(CN)4][Au2(CN)3] (3), [Cd(bishydeten)0,5]2[Au(CN)2]4.2H2O (4), and [Cd(bishydeten)2][Au(CN)2]2 (5) (where bisyhdeten = N,N-bis(2-hydroxyethyl)ethylene diamine), and their characterization by elemental, infrared, ESI-MS, X-ray (for 2) and thermic measurement methods were performed. Complexes 1 and 3 are thermally more stable than the … |
| Anahtar Kelimeler |
| Antiproliferative effect | Crystal structure | Cytotoxicity | Dicyanoaurate (I) | Spectroscopic titration |
Science Direct
Synthesis, characterization and anticancer activity in vitro evaluation of novel dicyanoaurate (I)-based complexes
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 3 |
| Scopus | 4 |
| Google Scholar | 6 |