The iron(III) and nickel(II) complexes with tetradentate thiosemicarbazones. Synthesis, experimental, theoretical characterization, and antiviral effect against SARS-CoV-2
Yazarlar (6)
Prof. Dr. Belkıs Atasever Arslan Üsküdar Üniversitesi, Türkiye
Arş. Gör. Buşra Kaya Istanbul University-Cerrahpasa, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Dr. Öğr. Üyesi Sefer Baday İstanbul Teknik Üniversitesi, Türkiye
Cemil Can Saylan
İstanbul Teknik Üniversitesi, Türkiye
İstanbul Teknik Üniversitesi, Türkiye
Bahri Ülküseven
Istanbul University-Cerrahpasa, Türkiye
Istanbul University-Cerrahpasa, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure (Q3) | ||
| Dergi ISSN | 0022-2860 Dergi Bilgileri (2021) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2021 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-12-2021 |
| Cilt / Sayı / Sayfa | 1246 / 1 / 131166–0 | DOI | 10.1016/j.molstruc.2021.131166 |
| Makale Linki | http://dx.doi.org/10.1016/j.molstruc.2021.131166 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
|
||
| Özet |
| The discovery of new inhibitors that can be used in the treatment of viral diseases, including Covid-19, is an area open to research, and there is a need for innovative compounds with increased efficiency that provide inhibition by suppressing enzyme, and receptor mechanisms. The iron(III) and nickel(II) complexes were synthesized by template condensation of 4-methoxy-salicylaldehyde with S-methylthiosemicarbazone derivatives of 1,1,1-trifluoroacetylacetone (for Fe1) and methylacetoacetate (for Ni1). The complex structures having N2O2-chelating thiosemicarbazidato ligand were identified by analytical, spectroscopic, and X-ray crystallography results. Coordination environment of iron(III) center in complex Fe1 has a distorted square pyramidal geometry consisting of the N2O2 donor set and a chlorine atom, while that of Ni1 is square plane with the set. Inhibitory effect of Fe1 compound against SARS-CoV-2 … |
| Anahtar Kelimeler |
| Iron | Nickel | SARS-CoV-2 | Thiosemicarbazone |
Science Direct
The iron(III) and nickel(II) complexes with tetradentate thiosemicarbazones. Synthesis, experimental, theoretical characterization, and antiviral effect against SARS-CoV-2
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 45 |
| Scopus | 45 |
| Google Scholar | 51 |