Synthesis, structural characterization and evaluation of anticancer activity of polymeric silver(I) complexes based on niflumic acid/naproxen and picoline derivatives
Yazarlar (6)
Prof. Dr. Sema Çağlar Erzincan Binali Yıldırım Üniversitesi, Türkiye
Prof. Dr. Ahmet Altay Erzincan Binali Yıldırım Üniversitesi, Türkiye
Betul Harurluoglu
Erzincan Binali Yıldırım Üniversitesi, Türkiye
Erzincan Binali Yıldırım Üniversitesi, Türkiye
Esma K. K. Yeniceri
Erzincan Binali Yıldırım Üniversitesi, Türkiye
Erzincan Binali Yıldırım Üniversitesi, Türkiye
Bülent Çağlar Erzincan Binali Yıldırım Üniversitesi, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Coordination Chemistry (Q3) | ||
| Dergi ISSN | 0095-8972 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Kabul Tarihi | 15-02-2022 | Yayınlanma Tarihi | 17-01-2022 |
| Cilt / Sayı / Sayfa | 75 / 1 / 178–196 | DOI | 10.1080/00958972.2022.2045586 |
| Makale Linki | http://dx.doi.org/10.1080/00958972.2022.2045586 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| Two polymeric mixed-ligand silver(I) complexes, [Ag(µ-nif)(4-pic)]n (1) and [Ag4(µ-nap)4(2-pic)2]n (2), where Hnif: niflumic acid, Hnap: naproxen, 4-pic: 4-picoline and 2-pic: 2-picoline, were synthesized and characterized by single-crystal X-ray diffraction, FT-IR and 1H NMR spectroscopies, elemental and thermal analysis techniques. In 1, nif ligand behaves as a µ3-N,O,O' bridge connecting three silver(I) ions and each silver(I) ion exhibits a seesaw geometry. In 2, nap ligands act as a µ-carboxylato-(O,O') bridge between two silver(I) ions and µ3-carboxylato-(O,O,O') bridge linking three silver(I) ions. Each silver(I) ion occurs in trigonal geometry. To uncover the anticancer properties of the complexes, first, their cytotoxic abilities were tested against three cancer cell lines, HT-29 (human colorectal adenocarcinoma), A-549 (human lung carcinoma), and MDA-MB-453 (human breast adenocarcinoma), and normal 3T3 … |
| Anahtar Kelimeler |
| apoptosis | cell culture | cytotoxicity | NSAIDs | Silver(I) |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 22 |
| Scopus | 22 |
| Google Scholar | 22 |