Zinc(II) coordination compound with N′-(pyridin-2-ylmethylene)nicotinohydrazide: Synthesis, crystal structure, computational and cytotoxicity studies
 
Yazarlar (10)
Suman Adhikari
Govt. Degree College, Hindistan
Sourav Nath
Govt. Degree College, Hindistan
Dr. Öğr. Üyesi Sevgi Kansız Samsun University, Türkiye
Nabajyoti Balidya
Milki High School, Hindistan
Anirban Kumar Paul
Cotton University, Hindistan
Prof. Dr. Necmi Dege Ondokuz Mayis University Faculty Of Science And Arts, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Ghodrat Mahmoudi
University Of Maragheh
Akalesh Kumar Verma
Cotton University, Hindistan
Damir A. Safin University Of Tyumen, Rusya Federasyonu
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Inorganic Biochemistry (Q1)
Dergi ISSN 0162-0134 Dergi Bilgileri (2024)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2024
Kabul Tarihi Yayınlanma Tarihi 01-08-2024
Cilt / Sayı / Sayfa 257 / 1 / 112598–0 DOI 10.1016/j.jinorgbio.2024.112598
Makale Linki https://doi.org/10.1016/j.jinorgbio.2024.112598
UAK Araştırma Alanları
Yoğun Madde Fiziği
Özet
In this work, we report on the synthesis of a novel zinc(II) coordination compound [ZnL2] (1), which was readily obtained from the reaction of Zn(OAc)·2H2O and N′-(pyridin-2-ylmethylene)nicotinohydrazide (HL) in methanol. Recrystallization of 1 from dimethylformamide under ambient conditions allowed to produce yellow block-like crystals of 1·H2O. Complex 1·H2O was characterized by FT-IR and 1H NMR spectroscopy, while its optical properties were studied by UV–vis and spectrofluorimetry in methanol. The crystal structure of the title complex was revealed by single crystal X-ray diffraction and further explored in detail by the Hirshfeld surface analysis. Theoretical investigations based on the DFT calculations have also been applied to show the electronic properties of complex 1. The antitumor activities of the parent ligand HL and complex 1 were studied using Dalton's lymphoma malignant cancer model. Both …
Anahtar Kelimeler
Crystal structure | Cytotoxicity | DFT | Molecular docking | Nicotinohydrazide | Zinc