A polymeric copper complex based on a pyrazole derivative: Synthesis, spectroscopic, X‐ray, and biological activity studies
Yazarlar (5)
Mina A. Amin
Faculty Of Science, Mısır
Faculty Of Science, Mısır
Dr. Öğr. Üyesi Halide Diker Ege Üniversitesi, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Prof. Dr. Canan Varlıklı Izmir Yüksek Teknoloji Enstitüsü, Türkiye
Ahmed A. Soliman
Faculty Of Science, Mısır
Faculty Of Science, Mısır
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Applied Organometallic Chemistry (Q1) | ||
| Dergi ISSN | 0268-2605 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2024 |
| Cilt / Sayı / Sayfa | 38 / 8 / – | DOI | 10.1002/aoc.7592 |
| Makale Linki | https://doi.org/10.1002/aoc.7592 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| A novel 1D coordination polymeric copper complex based on 4‐(4′‐nitrophenylhydrazono)‐5‐trifluoromethyl‐2,4‐dihydropyrazol‐3‐one was prepared and characterized spectroscopically and thermally and via X‐ray crystallographic investigation. The prepared copper‐based structure was proved to have a 1D coordination polymer. X‐ray studies showed that the polymeric copper complex was of octahedral geometry, the ligand acted as a bidentate ligand, and the nitro group attached to the ligand acted as a bridging group. The cytotoxic activities of the copper polymer were evaluated including against MCF‐7 cells (breast cancer cell line), HepG‐2 cells (hepatocellular carcinoma), and HCT‐116 cells (colon cancer cell line). The morphological alterations of the complex treated cells were investigated using an inverted microscope. The cell cycle and apoptosis were evaluated and reported. The copper polymer … |
| Anahtar Kelimeler |
| biological activity | copper polymer | ligand |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 4 |
| Scopus | 4 |
| Google Scholar | 5 |