Copper and nickel complexes based on 4-((4-nitrophenyl)diazenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol; synthesis, characterization, X-ray studies, DFT calculations, molecular docking and antimicrobial activity
Yazarlar (5)
Mina A. Amin
Faculty Of Science, Mısır
Faculty Of Science, Mısır
Dr. Öğr. Üyesi Halide Diker Ege Üniversitesi, Türkiye
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Prof. Dr. Canan Varlıklı Izmir Yüksek Teknoloji Enstitüsü, Türkiye
Ahmed A. Soliman
Faculty Of Science, Mısır
Faculty Of Science, Mısır
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Inorganic Chemistry Communications (Q1) | ||
| Dergi ISSN | 1387-7003 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2024 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-11-2024 |
| Cilt / Sayı / Sayfa | 169 / 1 / 113063–0 | DOI | 10.1016/j.inoche.2024.113063 |
| Makale Linki | https://doi.org/10.1016/j.inoche.2024.113063 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| Two new copper(II) and nickel(II) complexes were prepared using 4-((4-nitrophenyl)diazenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol (ndtp) and well-characterized spectroscopically and thermally and via X-ray studies. X-ray studies confirmed the formation of two octahedral complexes, containing two ndtp and two coordinated DMF molecules. The two complexes were evaluated in vitro against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus cereus. [Ni(ndtp)2(DMF)2] showed an enhanced antibacterial activity against the different bacterial strains compared to the free ligand and that of the [Cu(ndtp)2(DMF)2]. The mean inhibition zones exhibited by [Ni(ndtp)2(DMF)2] were 14.7±0.6, 14.0±1.0, and 16.3±0.6 mm against Escherichia coli, Staphylococcus aureus and Bacillus cereus, respectively. Molecular docking studies of the two complexes were performed with DNA gyrase of … |
| Anahtar Kelimeler |
| Antibacterial activity | Cu(II) and Ni(II) complexes | DFT | Docking | Pyrazole derivatives |
Science Direct
Copper and nickel complexes based on 4-((4-nitrophenyl)diazenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol; synthesis, characterization, X-ray studies, DFT calculations, molecular docking and antimicrobial activity
| Atıf Sayıları | |
| Web of Science | 3 |
| Scopus | 3 |
| Google Scholar | 3 |