Exploring the Antibacterial and Antibiofilm Efficacy of Psammogeton biternatum Edgew and Identification of a Novel Quinoline Alkaloid using X-ray Crystallography
Yazarlar (11)
Faiza Masood
Hazara University Pakistan, Pakistan
Hazara University Pakistan, Pakistan
Wajiha Khan
Comsats Islamabad, Pakistan
Comsats Islamabad, Pakistan
Imran Khan
Shaheed Benazir Bhutto University, Pakistan
Shaheed Benazir Bhutto University, Pakistan
Uzma Khan
Hazara University Pakistan, Pakistan
Hazara University Pakistan, Pakistan
Abdul Majid
Hazara University Pakistan, Pakistan
Hazara University Pakistan, Pakistan
Sebghat Ullah Khan
Hazara University Pakistan, Pakistan
Hazara University Pakistan, Pakistan
Prof. Dr. Onur ŞAHİN Sinop Üniversitesi, Türkiye
Aljawharah Alqathama
Umm Al-Qura University, Suudi Arabistan
Umm Al-Qura University, Suudi Arabistan
Muhammad Riaz
Shaheed Benazir Bhutto University, Pakistan
Shaheed Benazir Bhutto University, Pakistan
Rizwan Ahmad
Imam Abdulrahman Bin Faisal University, Suudi Arabistan
Imam Abdulrahman Bin Faisal University, Suudi Arabistan
Mohammad Mahtab Alam
King Khalid University, Suudi Arabistan
King Khalid University, Suudi Arabistan
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | ACS Omega (Q2) | ||
| Dergi ISSN | 2470-1343 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2024 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 15-10-2024 |
| Cilt / Sayı / Sayfa | 9 / 43 / 43557–43569 | DOI | 10.1021/acsomega.4c05459 |
| Makale Linki | https://doi.org/10.1021/acsomega.4c05459 | ||
| UAK Araştırma Alanları |
Yoğun Madde Fiziği
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| Özet |
| The prevalence of resistance to harmful human pathogens is steadily rising, emphasizing the urgent need to identify novel antimicrobial compounds. For this purpose, plants stand out as a significant source of bioactives worthy of exploration. Among these, alkaloids, a vast and structurally diverse category of plant secondary metabolites, have emerged as a foundation for crucial antibacterial medications such as metronidazole and the quinolones. In the current work, the crude methanol leaf extract of Psammogeton biternatum Edgew collected from District Bannu, Pakistan, was subjected to TLC (indirect) bioautography and X-ray crystallography for the isolation of potential antibacterial agents. From the crude extract, a novel quinoline alkaloid called quinoline dione ((3R,3aS,5aR)-3,5a,9-trimethyl-3a,4,5,5a-tetrahydro-2H-isoxazolo[2,3-a] quinoline-2,8(3H)-dione (C14H17NO3)) was isolated. The crystal information … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 4 |
| Scopus | 4 |
| Google Scholar | 3 |