Degradation and ecotoxicity of favipiravir and oseltamivir in the presence of microplastics during ozonation and catalytic ozonation of synthetic municipal wastewater effluents
Yazarlar (6)
Doç. Dr. Serdar Doğruel İstanbul Teknik Üniversitesi, Türkiye
Nasim Chavoshi
İstanbul Teknik Üniversitesi, Türkiye
Arş. Gör. Nilay BİLGİN SARITAŞ Sinop Üniversitesi, Türkiye
Prof. Dr. Alıreza Khataee İstanbul Teknik Üniversitesi, Türkiye
Doç. Dr. Emel Topuz Gebze Teknik Üniversitesi, Türkiye
Prof. Dr. Elif Pehlivanoğlu Mantaş İstanbul Teknik Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Chemical Technology and Biotechnology (Q3)
Dergi ISSN 0268-2575 Dergi Bilgileri (2025)
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 12-2025
Kabul Tarihi 03-02-2025 Yayınlanma Tarihi 20-02-2025
Cilt / Sayı / Sayfa 100 / 5 / 955–966 DOI 10.1002/jctb.7831
Makale Linki https://doi.org/10.1002/jctb.7831
UAK Araştırma Alanları
Su Kirliliği ve Kontrolü Çevre Kimyası Çevresel Toksikoloji
Özet
Background Favipiravir (FAV) and oseltamivir (OSE) are antiviral agents developed against influenza and they were repurposed against SARS‐CoV‐2 during the COVID‐19 pandemic. This study evaluated the potential of ozonation and catalytic ozonation as tertiary treatment approaches for removing FAV and OSE from municipal wastewaters, both in the presence and absence of microplastics (MPs), while comparing the ecotoxicity of untreated and treated secondary effluents to predict the ecotoxicological effects of these technologies during municipal wastewater treatment. Results At an initial antiviral concentration of 50 μg L−1, ozonation at pH 7 with a specific ozone dose of 0.6 mg O3 (mg DOC)−1 yielded FAV and OSE removals of 84 and 64%, respectively, while the presence of catalyst or MPs decreased the degradation rate by 30–40%. Raising the pH to 10 had minimal impact on FAV abatement, but …
Anahtar Kelimeler
catalytic ozonation | ecotoxicity | favipiravir | microplastics | oseltamivir | ozonation