Computational design and fabrication of a highly selective and sensitive molecularly imprinted electrochemical sensor for the detection of enzalutamide
Yazarlar (7)
S. Irem Kaya
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
Prof. Dr. Ahmet Cetinkaya Ankara Üniversitesi, Türkiye
Goksu Ozcelikay Ankara Üniversitesi, Türkiye
M. Emin Çorman Ankara Üniversitesi, Türkiye
Prof. Dr. Mustafa KARAKAYA Sinop Üniversitesi, Türkiye
Esen Bellur Atici Deva Holding A.S. R&D Center, Türkiye
Sibel A. Ozkan
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Electroanalytical Chemistry (Q1) | ||
| Dergi ISSN | 1572-6657 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-02-2022 |
| Cilt / Sayı / Sayfa | 907 / 1 / 1–9 | DOI | 10.1016/j.jelechem.2022.116030 |
| Makale Linki | http://dx.doi.org/10.1016/j.jelechem.2022.116030 | ||
| UAK Araştırma Alanları |
Atom, Molekül ve Lazer Fiziği
Spektroskopi
Optoelektronik
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| Özet |
| This study demonstrates the first electrochemical analysis of an anti-androgen drug enzalutamide with a molecularly imprinted polymer (MIP)-based sensor. An electrochemical sensor was developed through computational approaches for screening functional monomers in the rational design of MIPs. Based on the computational approach, ortho-phenylenediamine (o-PD) was selected as a functional monomer based on the comparison of interaction energies (ΔE) between enzalutamide and monomers. The characterization of the MIP-based sensor was investigated by Raman spectroscopy, surface electron microscopy (SEM), contact angle measurements, and electrochemical techniques. Different electrochemical techniques such as differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) were utilized for the evaluation of MIP parameters (removal process, incubation time … |
| Anahtar Kelimeler |
| Aniline | Drug analysis | Electrochemical determination | Enzalutamide | Molecularly imprinted polymer | O-phenylenediamine | Voltammetry |
Science Direct
Computational design and fabrication of a highly selective and sensitive molecularly imprinted electrochemical sensor for the detection of enzalutamide
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 24 |
| Scopus | 28 |
| Google Scholar | 30 |